Predictive Molecular Pathology in Lung Cancer (Ongoing)

Posted On 2021-07-05 15:27:56



This special series on “Predictive Molecular Pathology in Lung Cancer” is guest-edited by Prof. Umberto Malapelle and Prof. Ciancarlo Troncone from University of Naples Federico II, Italy, and aims to provide an updated overview of the most recent acquisitions and future perspectives.

Prof. Umberto Malapelle, PhD
Department of Public Health, University Federico II of Naples, Naples, Italy
PhD, Assistant Professor in Anatomic Pathology in School of Medicine, University of Naples Federico II
Currently is the Chief Supervisor of Predictive Molecular Pathology Laboratory, Department of Public Health of University Federico II of Naples.

His main research interest is in the field of genomic biomarkers validation and testing for predictive information in the field of lung cancer, metastatic colorectal cancer, melanoma and gastrointestinal stromal tumor.

Moreover, he has developed skills in tailoring Next Generation Assays for a number of different applications with a special focus on the simultaneously detection of clinical relevant alterations (i.e., EGFR mutations, ALK traslocation, PD–L1 expression) in the routine setting including handling of different sample types, such as tissues and/or liquid biopsy specimens.

Prof. Giancarlo Troncone, MD, PhD
Department of Public Health, University Federico II of Naples, Italy
MD, PhD, Full Professor of anatomic pathology, Director of the cytopathology unit, the molecular pathology unit, and the master’s degree program in predictive molecular pathology, Head of the Department of Public Health at the University of Naples Federico II in Naples, Italy.

He was trained in pathology at the Nuffield Department of Pathology, University of Oxford (Oxford, United Kingdom), and in cytopathology at the Department of Pathology and Laboratory Medicine, University of Pennsylvania (Philadelphia). His research interests include the development, validation, and quality assessment of a wide range of morpho-molecular techniques on cytopathologic specimens in the field of predictive pathology of solid tumors. He maintains an active cytodiagnostic practice, which includes lung, thyroid, lymph node, and breast samples.

Series outline:

Review Article on Predictive Molecular Pathology in Lung Cancer   
01. Lung Cancer Diagnosis
02. The Role of Cytolaptolgy in Predictive Molecular Pathology era
03. Sample Management for Biomarker Testing in Lung Cancer
04. Liquid Biopsy in Lung Cancer
05. Next Generation Technologies in Predictive Molecular Pathology
06. Conventional Molecular Biology Technologies in Predictive Molecular Pathology
07. Digital Pathology in Lung Cancer
08. Predictive Immuno-Histo Chemistry in Lung Cancer
09. Biomarkers to guide Target Therapy in NSCLC
10. Biomarkers to guide Immunotherapy in NSCLC
11. Interventional Radiology in NSCLC

Editorial on Predictive Molecular Pathology in Lung Cancer   
12. Predictive Molecular Pathology in Lung Cancer: The oncologist point of view
13. Predictive Molecular Pathology in Lung Cancer

Disclosure:
The special series “Predictive Molecular Pathology in Lung Cancer” was commissioned by the editorial office, Journal of Xiangya Medicine without any sponsorship or funding. Umberto Malapelle and Giancarlo Troncone are serving as the unpaid Guest Editors of the series.