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Low-dose interleukin-2 as a regulatoy immunetherapy for systemic lupus erythematosus

   
@article{JXYM3646,
	author = {Masayuki Mizui and George C. Tsokos},
	title = {Low-dose interleukin-2 as a regulatoy immunetherapy for systemic lupus erythematosus},
	journal = {Journal of Xiangya Medicine},
	volume = {1},
	number = {1},
	year = {2016},
	keywords = {},
	abstract = {Accumulating evidence that interleukin-2 (IL-2) is requisite for the maintenance and expansion of regulatory T cells (Treg) has yielded low-dose IL-2 therapy for several autoimmune diseases such as type 1 diabetes and systemic lupus erythematosus (SLE) (1,2). He and colleagues recently reported in Nat Med the efficacy of low-dose IL-2 treatment in 38 active SLE patients (3). They described that IL-2 treatment significantly ameliorated the clinical severity associated with expansion of Treg and decrease of follicular helper T (TFH) cells and IL-17-producing helper T (TH17) cells.},
	issn = {2519-9390},	url = {https://jxym.amegroups.org/article/view/3646}
}