The prostate cancer management dilemma: is it time to start a new era?

Prostate cancer is one of the most common lethal cancers in men in the developed countries. In the USA, it is estimated to affect 161,360 men (19% of all the newly diagnosed cancers) with an estimated mortality of 26,730 men (8% of all cancer deaths) in 2017. This renders it the most commonly diagnosed cancer and the third most common cause of cancer death in the USA in 2017 (1). Prostate cancer is an unique malignancy in that most of patients die with and not because of it (2).